
Itinerary Details
Select the week and day to view day-by-day itineraries for this voyage.
Arrives
Monday, 10 November 2025Location
Programme
Choose your sightseeing this morning, then be transferred to your river ship. Set sail from My Tho and soak up the scenery during your cruise towards Cai Be. Tonight, a Vietnamese welcome dinner awaits, showcasing the diverse flavours from the region.
Freedom of Choice – City Walking Tour
Discover the city’s iconic landmarks and French colonial architecture on an informative guided walk. Stroll by the Saigon Opera House, Central Post Office and Notre Dame Cathedral.
Freedom of Choice – Motorbike Ride
Jump on the back of a motorbike like a local for a thrilling sightseeing adventure. Weave through the streets past the Central Post Office and Independence Palace. Visit Chinatown and Thien Hau pagoda.
Freedom of Choice – Cooking Class
Meet your chef, visit the market and discover Vietnamese ingredients. Continue to a villa and relax in the outdoor garden before you create your dishes. Learn the intricacies of making bánh mì xíu mại.
Freedom of Choice – Ho Chi Minh City Shopping Adventure
Seek out the city’s boutiques and discover high-quality handmade goods on a visit to Mekong Quilts. Saigon Kitsch sells quirky souvenirs, while L’Usine is a trend-setting lifestyle store.
Arrives
Tuesday, 11 November 2025Location
Programme
Board your traditional sampan for your first excursion on the banks of the Mekong. Step ashore to visit French gothic Cai Be Church, built in the Roman architectural style, as well as the colourful port area filled with crumbling colonial buildings and flowering gardens. The church’s bell tower, with its set of four bells cast in France in 1931, is the tallest bell tower in the Tien Giang Province. Afterwards, you’ll visit rice paper and coconut candy manufacturers and learn how these Vietnamese staples are made.
Head back to the ship to refresh before sitting down to savour a delicious lunch whilst continuing to cruise to the quaint town of Sa Dec. Upon arrival, explore Sa Dec by foot and meet some of the sellers at the colourful market. Continue to where French writer Marguerite Duras met her Vietnamese-Chinese lover, Huynh Thuy Le. Tour his former home and learn the story behind Duras’ best-selling novel, ‘The Lover’. After, visit a traditional Cao Dai temple. Watch visitors and pilgrims come and go and appreciate the beauty of the colourful building. Sail towards Tan Chai as dinner is served.
Arrives
Wednesday, 12 November 2025Location
Programme
Transfer to a small boat to cruise the tiny tributaries around the town of Tan Chau. Disembark for a rickshaw tour and visit a local silk and rattan weaving workshop. Then, explore Evergreen Island to see authentic rural Mekong life. This afternoon, appreciate some downtime and watch the scenery pass as the Mekong Serenity cruises towards the Cambodian border.
Arrives
Thursday, 13 November 2025Location
Programme
Enjoy your Freedom of Choice activity, then spend the remainder of the afternoon at leisure. You may wish to head ashore and explore more of Phnom Penh independently or simply relax on board.
Freedom of Choice – Killing Fields and Genocide Museum
Learn about a confronting part of Cambodian history during a sobering visit to the Killing Fields and Tuol Sleng Genocide Museum.
Freedom of Choice – Cyclo Ride
Explore Phnom Penh by what was the most popular form of transportation throughout Southeast Asia in the 1960s, the cyclo. Weave past some of the city’s most iconic sites.
Freedom of Choice – Visit the National Museum
Accompanied by your private museum guide, discover the most important pieces within the National Museum of Cambodia. The collection includes the world’s finest display of Khmer sculptures, art and relics.
Freedom of Choice – Royal Palace and Silver Pagoda
Discover Cambodia’s Royal Palace, the official residence of the King. Completed in 1870, the palace is an extraordinary example of Khmer architecture with elements of French influence. The palace also houses the Silver Pagoda.
Arrives
Friday, 14 November 2025Location
Programme
Journey to Oudong, Cambodia’s former royal capital, where you will enjoy a Signature Experience. Following the visit, return via Koh Chen village and visit local copperware workshops. Back on board, cruise to Oknha Tey, known for its silk weaving traditions. Stroll among the stilt houses and gain an insight into the traditional silk weaving process. Watch as the village women create beautiful Khmer fabrics from their wooden looms.
Signature Experience – Buddhist Blessing Ceremony
Take part in a traditional Buddhist blessing ceremony for good luck, health and safe journey, with resident monks at a monastery in Oudong.
Arrives
Saturday, 15 November 2025Location
Programme
Sail to Angkor Ban, where you'll disembark and enjoy a captivating walking discovery of this historic village. Remarkably, Angkor Ban stands as one of the rare Cambodian villages that remained unscathed during the tumultuous Khmer Rouge regime of the 1970s. Here, people still live in traditional wooden homes and keep ancient cultural traditions alive. This afternoon, your ship continues sailing upstream to Wat Hanchey.
Arrives
Sunday, 16 November 2025Location
Programme
If you are feeling active this morning, walk to the hilltop pagoda of Wat Hanchey for expansive views over the Mekong. Here, you may find some novice monks along with many temples, pagodas, and stupas, some built this century while others date back to the eighth century. Savour lunch on board before enjoying a Signature Experience. Celebrate with a farewell dinner on board this evening.
Signature Experience – Tuk Tuk Tour of Koh Pen
Journey by local tuk tuk around a riverside village and gain an insight into village life. Travel along the shaded lanes past stilted houses and see a varying range of crops growing.
Arrives
Monday, 10 November 2025Location
Programme
Choose your sightseeing this morning, then be transferred to your river ship. Set sail from My Tho and soak up the scenery during your cruise towards Cai Be. Tonight, a Vietnamese welcome dinner awaits, showcasing the diverse flavours from the region.
Freedom of Choice – City Walking Tour
Discover the city’s iconic landmarks and French colonial architecture on an informative guided walk. Stroll by the Saigon Opera House, Central Post Office and Notre Dame Cathedral.
Freedom of Choice – Motorbike Ride
Jump on the back of a motorbike like a local for a thrilling sightseeing adventure. Weave through the streets past the Central Post Office and Independence Palace. Visit Chinatown and Thien Hau pagoda.
Freedom of Choice – Cooking Class
Meet your chef, visit the market and discover Vietnamese ingredients. Continue to a villa and relax in the outdoor garden before you create your dishes. Learn the intricacies of making bánh mì xíu mại.
Freedom of Choice – Ho Chi Minh City Shopping Adventure
Seek out the city’s boutiques and discover high-quality handmade goods on a visit to Mekong Quilts. Saigon Kitsch sells quirky souvenirs, while L’Usine is a trend-setting lifestyle store.
Arrives
Tuesday, 11 November 2025Location
Programme
Board your traditional sampan for your first excursion on the banks of the Mekong. Step ashore to visit French gothic Cai Be Church, built in the Roman architectural style, as well as the colourful port area filled with crumbling colonial buildings and flowering gardens. The church’s bell tower, with its set of four bells cast in France in 1931, is the tallest bell tower in the Tien Giang Province. Afterwards, you’ll visit rice paper and coconut candy manufacturers and learn how these Vietnamese staples are made.
Head back to the ship to refresh before sitting down to savour a delicious lunch whilst continuing to cruise to the quaint town of Sa Dec. Upon arrival, explore Sa Dec by foot and meet some of the sellers at the colourful market. Continue to where French writer Marguerite Duras met her Vietnamese-Chinese lover, Huynh Thuy Le. Tour his former home and learn the story behind Duras’ best-selling novel, ‘The Lover’. After, visit a traditional Cao Dai temple. Watch visitors and pilgrims come and go and appreciate the beauty of the colourful building. Sail towards Tan Chai as dinner is served.
Arrives
Wednesday, 12 November 2025Location
Programme
Transfer to a small boat to cruise the tiny tributaries around the town of Tan Chau. Disembark for a rickshaw tour and visit a local silk and rattan weaving workshop. Then, explore Evergreen Island to see authentic rural Mekong life. This afternoon, appreciate some downtime and watch the scenery pass as the Mekong Serenity cruises towards the Cambodian border.
Arrives
Thursday, 13 November 2025Location
Programme
Enjoy your Freedom of Choice activity, then spend the remainder of the afternoon at leisure. You may wish to head ashore and explore more of Phnom Penh independently or simply relax on board.
Freedom of Choice – Killing Fields and Genocide Museum
Learn about a confronting part of Cambodian history during a sobering visit to the Killing Fields and Tuol Sleng Genocide Museum.
Freedom of Choice – Cyclo Ride
Explore Phnom Penh by what was the most popular form of transportation throughout Southeast Asia in the 1960s, the cyclo. Weave past some of the city’s most iconic sites.
Freedom of Choice – Visit the National Museum
Accompanied by your private museum guide, discover the most important pieces within the National Museum of Cambodia. The collection includes the world’s finest display of Khmer sculptures, art and relics.
Freedom of Choice – Royal Palace and Silver Pagoda
Discover Cambodia’s Royal Palace, the official residence of the King. Completed in 1870, the palace is an extraordinary example of Khmer architecture with elements of French influence. The palace also houses the Silver Pagoda.
Arrives
Friday, 14 November 2025Location
Programme
Journey to Oudong, Cambodia’s former royal capital, where you will enjoy a Signature Experience. Following the visit, return via Koh Chen village and visit local copperware workshops. Back on board, cruise to Oknha Tey, known for its silk weaving traditions. Stroll among the stilt houses and gain an insight into the traditional silk weaving process. Watch as the village women create beautiful Khmer fabrics from their wooden looms.
Signature Experience – Buddhist Blessing Ceremony
Take part in a traditional Buddhist blessing ceremony for good luck, health and safe journey, with resident monks at a monastery in Oudong.
Arrives
Saturday, 15 November 2025Location
Programme
Sail to Angkor Ban, where you'll disembark and enjoy a captivating walking discovery of this historic village. Remarkably, Angkor Ban stands as one of the rare Cambodian villages that remained unscathed during the tumultuous Khmer Rouge regime of the 1970s. Here, people still live in traditional wooden homes and keep ancient cultural traditions alive. This afternoon, your ship continues sailing upstream to Wat Hanchey.
Arrives
Sunday, 16 November 2025Location
Programme
If you are feeling active this morning, walk to the hilltop pagoda of Wat Hanchey for expansive views over the Mekong. Here, you may find some novice monks along with many temples, pagodas, and stupas, some built this century while others date back to the eighth century. Savour lunch on board before enjoying a Signature Experience. Celebrate with a farewell dinner on board this evening.
Signature Experience – Tuk Tuk Tour of Koh Pen
Journey by local tuk tuk around a riverside village and gain an insight into village life. Travel along the shaded lanes past stilted houses and see a varying range of crops growing.
Arrives
Monday, 17 November 2025Location
Programme
Bid farewell to the crew and disembark the Mekong Serenity early at Kampong Cham. Travel to Siem Reap, the gateway to Angkor Wat, passing through picturesque countryside and remote villages, where you can observe rural life. On arrival at your hotel, enjoy a light lunch and some relaxation time before a Signature Experience. Later, indulge in another captivating Signature Experience.
Signature Experience – Local Charity Visit
Visit Opportunities of Development through Art (ODA), a OneTomorrow partner. ODA provides free English education and an introduction to computer skills to children living in Siem Reap’s remote villages, with the aim to improve future employment opportunities.
Signature Experience – VIP Circus Show and Backstage Visit
Be welcomed backstage at Phare Circus to meet some of the performers and witness a mesmerising performance from your VIP seats. This unforgettable spectacle showcases the country’s rich culture and talent by combining captivating acrobatics, theatre, and storytelling.
Arrives
Monday, 17 November 2025Location
Programme
Bid farewell to the crew and disembark the Mekong Serenity early at Kampong Cham. Travel to Siem Reap, the gateway to Angkor Wat, passing through picturesque countryside and remote villages, where you can observe rural life. On arrival at your hotel, enjoy a light lunch and some relaxation time before a Signature Experience. Later, indulge in another captivating Signature Experience.
Signature Experience – Local Charity Visit
Visit Opportunities of Development through Art (ODA), a OneTomorrow partner. ODA provides free English education and an introduction to computer skills to children living in Siem Reap’s remote villages, with the aim to improve future employment opportunities.
Signature Experience – VIP Circus Show and Backstage Visit
Be welcomed backstage at Phare Circus to meet some of the performers and witness a mesmerising performance from your VIP seats. This unforgettable spectacle showcases the country’s rich culture and talent by combining captivating acrobatics, theatre, and storytelling.
Mekong serenity

Featuring just 44 spacious suites with deluxe queen-size beds, sitting areas, spacious en suites, floor to ceiling windows, an indoor panoramic balcony and outside private balcony.
Relish a six-course Southeast Asian degustation at the intimate Indochine Restaurant, enjoy superb cuisine at Lemongrass Restaurant, and relax in the Harmony Lounge and Horizon Pool Bar & Grill.
During your cruise, wake up to freshly baked pastries and juices. Enjoy a selection of international wines, local spirits, and specialty teas and coffee.
Immerse yourself in our onboard experiences. From local guide presentations and cooking demonstrations to vegetable carvings and fruit tasting. Enjoy talent shows and traditional dance performances..
Unwind in the refreshing outdoor pool, ideal for cooling off. Marvel at tranquil views of the Mekong River just steps away from the bar.
Indulge in our wellness areas on board. Rejuvenate with a massage and facial at our onboard spa or stay active in the Fitness Centre.
Please note: There are no children's facilities on board.
Featuring just 44 spacious suites with deluxe queen-size beds, sitting areas, spacious en suites, floor to ceiling windows, an indoor panoramic balcony and outside private balcony.
Relish a six-course Southeast Asian degustation at the intimate Indochine Restaurant, enjoy superb cuisine at Lemongrass Restaurant, and relax in the Harmony Lounge and Horizon Pool Bar & Grill.
During your cruise, wake up to freshly baked pastries and juices. Enjoy a selection of international wines, local spirits, and specialty teas and coffee.
Immerse yourself in our onboard experiences. From local guide presentations and cooking demonstrations to vegetable carvings and fruit tasting. Enjoy talent shows and traditional dance performances..
Unwind in the refreshing outdoor pool, ideal for cooling off. Marvel at tranquil views of the Mekong River just steps away from the bar.
Indulge in our wellness areas on board. Rejuvenate with a massage and facial at our onboard spa or stay active in the Fitness Centre.
Please note: There are no children's facilities on board.
Accommodation Options

Angkor Suite (AS)
Welcome to the Angkor Suite aboard the Mekong Serenity from APT Guided Tours & River Cruises, your home away from home. Your private abode includes a range of amenities for your enjoyment, relaxation and comfort. The thoughtfully presented suite provides a wonderful space to relax after another fulfilling day exploring the world's waterways. Discover the full details and specifications below.

Bayon Suite (BS)
Welcome to the Bayon Suite aboard the Mekong Serenity from APT Guided Tours & River Cruises, your home away from home. Your private abode includes a range of amenities for your enjoyment, relaxation and comfort. The thoughtfully presented suite provides a wonderful space to relax after another fulfilling day exploring the world's waterways. Discover the full details and specifications below.

Deluxe Twin Balcony Suite (EE, D, C, A, B, E)
Welcome to the Deluxe Twin Balcony Suite aboard the Mekong Serenity from APT Guided Tours & River Cruises, your home away from home. Your private abode includes a range of amenities for your enjoyment, relaxation and comfort. The thoughtfully presented suite provides a wonderful space to relax after another fulfilling day exploring the world's waterways. Discover the full details and specifications below.
Deck Plans
- Lemongrass Restaurant
- Category C cabin
- Category D cabin
Category E cabin

- Indochine Private Dining
- Reception
- Harmony Lounge & Bar
- Category A cabin
- Category B cabin

- Swimming Pool
- Horizon Pool
- Bar & Grill
- Gym
- Angkor Suite
- Bayon Suites

- Sun Deck

- Lemongrass Restaurant
- Category C cabin
- Category D cabin
Category E cabin

- Indochine Private Dining
- Reception
- Harmony Lounge & Bar
- Category A cabin
- Category B cabin

- Swimming Pool
- Horizon Pool
- Bar & Grill
- Gym
- Angkor Suite
- Bayon Suites

- Sun Deck
